Donor Name: International Development Research Centre (IDRC), Centre de recherché pour de developpement International
Fund name: Livestock Vaccine Innovation Fund
Funding brief: The Livestock Vaccine Innovation Fund (LVIF) is an initiative developed by the Bill & Melinda Gates Foundation, Global Affairs Canada and Canada’s International Development Research Centre. It represents a joint investment of CA$ 57 million over five years to support the development, production, and commercialization of innovative vaccines against livestock diseases (including poultry) in sub-Saharan Africa, South and South East Asia. The LVIF will work through partnerships to develop vaccines that are affordable, available, and acceptable to livestock smallholders and to facilitate their use at scale. The Fund targets key livestock diseases that have the most impact on both women and men livestock smallholders.
The second global competitive call has been designed to achieve one of the goals of the program, which is to support technological innovations to improve livestock vaccines for smallholders in sub-Saharan Africa, South and South-east Asia.
Research to be supported by this Call:Research supported by this call will comprise of novel ideas or pre-existing innovations to respond to the challenges of existing livestock vaccines in Sub-Saharan Africa and South and Southeast Asia. Proposed research will be expected to focus on generating vaccines with better product profiles and must demonstrate high potential for adoption by vaccine manufacturers and livestock smallholders.
This call seeks proposals that are adopting innovative approaches to increase the duration of immunity by better induction and maintenance of immunological memory, reduce the number primo-vaccinations and/or revaccinations, improve vaccine safety and develop universal vaccines with capacity to provide protection against multiple strains, subtypes or serotypes. Examples of research eligible for this call include in silico prediction of virulent or immunogenic genes and subsequent application of these to develop safe, stable but highly effective vaccines, targeted delivery of vaccines by use of novel adjuvants or cytokines to generate the desired immune response, formulation of vaccines with appropriate carriers to generate effective mucosal immunity or eliminate parenteral administration. In addition, rapid platforms to predict and generate vaccines that can protect against multiple serotypes will be considered. Where applicable, innovations from other medical or veterinary fields could be harnessed to provide new mechanisms to deliver vaccines to maintain circulating antibodies against specific pathogens during windows of susceptibility or eliminate the need for revaccination.
The results of these projects will be the discovery of new adjuvants/vaccine delivery systems and novel vaccine design/formulations that present significant improvements over current vaccines and which can be transferred to vaccine manufacturers for subsequent registration of commercial vaccines for the livestock diseases listed in Appendix 1.
Research teams will need to present a compelling justification for the proposed innovative approach. Specifically, teams should describe why previous work targeting the proposed improvement have not been successful and explain why they believe the proposed innovation will be successful. In addition, it is essential for research teams to demonstrate strong capacity to generate timely results based on specific milestones and within the allocated budget.
Deadline: March 21, 2017 at 12:00pm EDT (Ottawa)
Funding details link: https://www.idrc.ca/en/funding/grants/innovations-improve-livestock-vaccines
Budget limit: intend to provide grant funding for up to 6 research projects of up to a maximum of CA$ 1,000,000 each. Contribution in the form of co-funding and mobilization of third party resources (public or private sector, other donor or stakeholder funding, etc.) to support and expand the research is encouraged.
Project start date: Not Found
Project duration: Up to 30 months.
Eligible organization: As below
Eligibility: The proposed research must focus on vaccine improvement for one or more of the eligible livestock diseases of the LVIF as specified in Annex 1.
● Applicants from academia, private and public sector organizations with a strong research focus are eligible for this global call.
● Applicants from the United Nations system cannot apply to this Call as lead or co-applicants. UN organizations may participate as collaborating organizations.
● Applicants from CGIAR Centres are not eligible as lead applicant but are eligible as co-applicants or collaborating organizations.
● The lead applicant and co-applicants may negotiate and develop funding arrangements directly with third-party organizations for specific services. IDRC will not contract directly with third-party organizations. Applications that involve third-party organizations must clearly justify their involvement and explain their role(s). The total third-party participation in a project is set at a maximum of 30% of the budget.
● A person cannot be the lead applicant for more than one project. At most, person can apply as the lead applicant for one project and be a co-applicant for two additional projects.
Submission mail: Not Found
Other important link:
● Guideline: https://lvif-fivb.fluidreview.com/pm/resource/eyJoZnJlIjogMTcyMjgsICJ2cSI6IDcwNTY5fQ/
● FAQ: https://lvif-fivb.fluidreview.com/pm/resource/eyJoZnJlIjogOTI3Mjc4NjIsICJ2cSI6IDcwNjA3fQ/
● Apply online: https://lvif-fivb.fluidreview.com/
● Guidelines for acceptable project expenditures: https://www.idrc.ca/sites/default/files/sp/Documents%20EN/resources/idrc-guidelines-for-acceptable-project-expenditures.pdf
Some useful links addressing Canadian and International Environmental Safety Standards are provided below.
● World Organization for animal health (OIE):http://www.oie.int/en/international-standard-setting/terrestrial-manual/access-online/
● CEAA, 2012: https://www.ceaa-acee.gc.ca/default.asp?lang=En&n=A4C57835-1
● World Health Organization (WHO) :http://www.who.int/biologicals/vaccines/good_manufacturing_practice/en/
● OECD: http://www.oecd.org/chemicalsafety/testing/goodlaboratorypracticeglp.htm
● European Commission:http://ec.europa.eu/health/documents/eudralex/vol-4/index_en.htm
How to apply: IDRC invites eligible applicants to submit an electronic application through IDRC’s grant application submission system (https://lvif-fivb.fluidreview.com/) to this Call for Research Proposals.
Applications can be submitted in either English or French.
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